Higher Bmi Is Associated With Lower Mortality Risk In Patients With Severe Ph

“A possible mechanism underlying this phenomenon is increased levels of serum lipoproteins associated with increased body fat, which may play a role in neutralizing circulating toxins and inflammatory proteins.” ### * Please note that numbers in this release may differ slightly from those in the abstract. Many of these investigations are ongoing; the release http://www.kunyit.my/benefits-of-taking-curcumin-supplement-daily represents the most up-to-date data available at press time. Abstract 54123 Mortality In Patients With Pulmonary Hypertension And High Body Mass Index Type: Scientific Abstract Category: 18.10 – Pulmonary Hypertension: Clinical Treatment and Outcomes (PC) Authors: J.D. Caceres1, M.K. Mojadidi1, P. Eshtehardi1 R. Zolty1; 1Jacobi Medical Center/Albert Einstein College of Medicine – Bronx, NY/US Abstract Body Background/Rationale Contrary to the conventional view that a lower body mass index (BMI) results in better health, recent studies suggest that obesity and a larger waist size have a favorable effect on the prognosis of patients with congestive heart failure. While obesity is a known risk factor for heart disease and heart failure, being overweight may provide some protective benefits. This is known as the “obesity paradox phenomenon”. Obesity hypoventilation syndrome and sleep apnea have been well described as causes of pulmonary hypertension. However, there is currently a paucity of data on BMI as a predictor of outcomes in pulmonary hypertension (PH). The aim of this study was to determine whether an obesity paradox occurs in patients with severe PH. Methods From July 2002 to July 2012, the transthoracic echos of all patients were reviewed to find patients with severe pulmonary hypertension defined by a pulmonary artery systolic pressure > 60 mmHg. All patients with an ejection fraction < 50% were excluded from the study. Patients were divided into three groups stratified by their BMI: Group A: Severe PH resource with a normal BMI (18 to 24.9 kg/m2) Group B: Severe PH with obesity (BMI 25 to 39.9 kg/m2) Group C: Severe PH with morbid obesity (BMI 40 kg/m2) Inpatient and social security death records were used to determine one-year mortality.
To continue reading ‘Higher BMI is associated with lower mortality risk in patients with severe PH’, visit http://www.eurekalert.org/pub_releases/2014-05/ats-hbi051214.php


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